Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Hypoxic Preconditioning Averts Sporadic Alzheimer's Disease-Like Phenotype in Rats: A Focus on Mitochondria.

Antioxidants & redox signaling - 1 Oct 2022

Correia Sónia C, Alves Marco G, Oliveira Pedro F, Casadesus Gemma, LaManna Joseph, Perry George, Moreira Paula I

Abstract excerpt

Aims: Brief episodes of sublethal hypoxia reprogram brain response to face possible subsequent lethal stimuli by triggering adaptive and prosurvival events-a phenomenon denominated hypoxic preconditioning (HP). To date, the potential therapeutic implications of HP to forestall sporadic Alzheimer's disease (sAD) pathology remain unexplored. Using a well-established protocol of HP and focusing on hippocampus as a...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Glial Fibrillary Acidic Protein
Share to Glutamates

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Hypoxia

Share to Inositol

Share to Lactates

Share to Mitochondria

Share to Streptozocin

Share to Succinates

Source

Identifiers

PMID: 35316086
DOI: 10.1089/ars.2019.8007

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Hypoxic Preconditioning Averts Sporadic Alzheimer's Disease-Like Phenotype in Rats: A Focus on Mitochondria.PMID 35316086Read ↗

Mitochondrial Targeting against Alzheimer’s Disease: Lessons from HibernationSemantic proximity Read ↗

Adaptive preconditioning in neurological diseases – therapeutic insights from proteostatic perturbationsSemantic proximity Read ↗

The 40 Hz flickering light restores synaptic plasticity and mitochondrial phenotype in experimental model of Alzheimer’s diseaseSemantic proximity Read ↗

Decreased accumulation of subcellular amyloid-β with improved mitochondrial function mediates the neuroprotective effect of huperzine A.Semantic proximity Read ↗

Endogenous reactive oxygen species cause astrocyte defects and neuronal dysfunctions in the hippocampus: a new model for aging brain.Semantic proximity Read ↗

Are Hippocampal Hypoperfusion and ATP Depletion Prime Movers in the Genesis of Alzheimer’s Disease? A Review of Recent Pertinent Observations from Molecular BiologySemantic proximity Read ↗

Are Hippocampal Hypoperfusion and ATP Depletion Prime Movers in the Genesis of Alzheimer’s Disease? A Review of Recent Pertinent Observations from Molecular BiologySemantic proximity Read ↗

Sevoflurane exposure accelerates the onset of cognitive impairment via promoting p-Drp1S616-mediated mitochondrial fission in a mouse model of Alzheimer's diseaseSemantic proximity Read ↗

The Role of Oxygen Homeostasis and the HIF-1 Factor in the Development of NeurodegenerationSemantic proximity Read ↗

Remote Ischemic Conditioning Alleviates Alzheimer’s Disease Pathology in Female TgF344 RatsSemantic proximity Read ↗

Mitochondrial Transfer Ameliorates Cognitive Deficits, Neuronal Loss, and Gliosis in Alzheimer’s Disease MiceSemantic proximity Read ↗

Inhibition of Autophagy Prevents Hippocampal Pyramidal Neuron Death after Hypoxic-Ischemic InjurySemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.