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Mitochondrial Targeting against Alzheimer’s Disease: Lessons from Hibernation

20 Dec 2023

Abstract excerpt

Alzheimer's disease (AD) is the most common cause of dementia worldwide and yet remains without effective therapy. Amongst the many proposed causes of AD, the mitochondrial cascade hypothesis is gaining attention. Accumulating evidence shows that mitochondrial dysfunction is a driving force behind synaptic dysfunction and cognitive decline in AD patients. However, therapies targeting the mitochondria in AD have...

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PMID: 38201215
DOI: 10.3390/cells13010012

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