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Article

Effect of LncRNA XIST on Immune Cells of Primary Biliary Cholangitis

4 Mar 2022

Abstract excerpt

Objective: Primary biliary cholangitis (PBC) is an autoimmune disease with significant gender difference. X chromosome inactivation (XCI) plays important roles in susceptibility to diseases between genders. This work focuses on the differences of LncRNA XIST in several defined immune cells populations as well as its effects on naive CD4+ T cells proliferation and differentiation in patients with PBC. Methods:...

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PMID: 35309298
DOI: 10.3389/fimmu.2022.816433

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