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The Role of Long Noncoding RNA BST2-2 in the Innate Immune Response to Viral Infection

17 Mar 2022

Abstract excerpt

Innate immunity is an important part of the human immune system to resist the invasion of foreign pathogens. IRF3 plays a critical role in the innate immune response to viral infection. In this study, we demonstrated that lncBST2-2 plays an important role in innate immunity. Virus-induced lncBST2-2 positively regulates innate immunity by interacting with IRF3 and blocking the dephosphorylation effect of...

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PMID: 35297670
DOI: 10.1128/jvi.00207-22

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