Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

TNFRSF1B and TNF Variants Are Associated With Differences in Levels of Soluble Tumor Necrosis Factor Receptors in Patients With Severe COVID-19.

The Journal of infectious diseases - 13 Sept 2022

Fricke-Galindo Ingrid, Buendía-Roldán Ivette, Ruiz Andy, Palacios Yadira, Pérez-Rubio Gloria, de Jesus Hernández-Zenteno Rafael, Reyes-Melendres Felipe, Zazueta-Márquez Armando, Alarcón-Dionet Aimé, Guzmán-Vargas Javier, Bravo-Gutiérrez Omar Andrés, Quintero-Puerta Teresa, Gutiérrez-Pérez Ilse Adriana, Nava-Quiroz Karol J, Bañuelos-Flores José Luis, Mejía Mayra, Rojas-Serrano Jorge, Ramos-Martínez Espiridión, Guzmán-Guzmán Iris Paola, Chávez-Galán Leslie, Falfán-Valencia Ramcés

Abstract excerpt

BACKGROUND: The impact of genetic variants in the expression of tumor necrosis factor-α (TNF-α) and its receptors in coronavirus disease 2019 (COVID-19) severity has not been previously explored. We evaluated the association of TNF (rs1800629 and rs361525), TNFRSF1A (rs767455 and rs1800693), and TNFRSF1B ( and ) variants with COVID-19 severity, assessed as invasive mechanical ventilation (IMV)...

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to COVID-19
Share to COVID-19 Clinical Research Studies
Share to Genotype
Share to Immune Response and Inflammation
Share to Receptors, Tumor Necrosis Factor, Type I
Share to Receptors, Tumor Necrosis Factor, Type II
Share to Respiratory Support and Mechanisms
Share to Tumor Necrosis Factor-alpha

Source

Open in PubMed Open full text

Identifiers

PMID: 35294530
DOI: 10.1093/infdis/jiac101
PMCID: PMC8992340

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

TNFRSF1B and TNF Variants Are Associated With Differences in Levels of Soluble Tumor Necrosis Factor Receptors in Patients With Severe COVID-19.PMID 35294530Read ↗

Association of polymorphisms in tumor necrosis factors with SARS-CoV-2 infection and mortality rate: A case-control study and in silico analyses.Semantic proximity Read ↗

Association of pro-inflammatory and anti-inflammatory cytokine polymorphisms with COVID-19 severity in unvaccinated patientsSemantic proximity Read ↗

Association of IL-10-592 C > A /-1082 A > G and the TNFα -308 G > A with susceptibility to COVID-19 and clinical outcomes.Semantic proximity Read ↗

Molecular Determination of Tumor Necrosis Factor-alpha, Interleukin-8, Interleukin-10, and C-X-C Chemokine Receptor-2 Genetic Variations and their Association with Disease Susceptibility and Mortality in COVID-19 PatientsSemantic proximity Read ↗

Association of TNF-α-308G/A Gene Polymorphism with Coronavirus Disease-19 SeveritySemantic proximity Read ↗

Single nucleotide polymorphisms located in TNFA, IL1RN, IL6R, and IL6 genes are associated with COVID-19 risk and severity in an Iranian population.Semantic proximity Read ↗

Association of the IL6 rs1800795 polymorphism with COVID-19 clinical severity in a Brazilian population.Semantic proximity Read ↗

Implication of IL-12A, IL-12B, IL-6, and TNF single-nucleotide polymorphisms in severity and susceptibility to COVID-19.Semantic proximity Read ↗

Association of TNF-α G-308 a Promoter Polymorphism with the Course and Outcome of COVID-19 Patients.Semantic proximity Read ↗

The TNFRSF13C H159Y Variant Is Associated with Severe COVID-19: A Retrospective Study of 500 Patients from Southern Italy.Semantic proximity Read ↗

Cytokine storm polymorphisms in nonvaccinated COVID-19 patientsSemantic proximity Read ↗

Influence of inflammatory and reninangiotensin system gene polymorphisms ACE2 rs2285666, IL1A rs1800587, and TNF rs1800629 on COVID-19 severity and the persistence of symptoms in the post-COVID-19 phase: a cross-sectional study.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.