Association of polymorphisms in tumor necrosis factors with SARS-CoV-2 infection and mortality rate: A case-control study and in silico analyses.

doi:10.1002/jmv.27477

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Article

Association of polymorphisms in tumor necrosis factors with SARS-CoV-2 infection and mortality rate: A case-control study and in silico analyses.

Journal of medical virology - 1 Apr 2022

Heidari Nia Milad, Rokni Mohsen, Mirinejad Shekoufeh, Kargar Maryam, Rahdar Sara, Sargazi Saman, Sarhadi Mohammad, Saravani Ramin

Abstract excerpt

The present coronavirus disease 2019 (COVID-19) is spreading rapidly and existing data has suggested a number of susceptibility factors for developing a severe course of the disease. The current case-control experiment is aimed to study the associations of genetic polymorphisms in tumor necrosis...

Topics

Adult
Aged
Alleles
COVID-19
Case-Control Studies
Computer Simulation
Female
Genetic Predisposition to Disease
Humans
Iran
Logistic Models
Lymphotoxin-alpha
Male
Middle Aged
Polymorphism, Single Nucleotide

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Identifiers

PMID: 34821383
DOI: 10.1002/jmv.27477
PMCID: PMC9015227

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-34821383-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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Tumor Necrosis Factor-alpha