Article
Association of IL-10-592 C > A /-1082 A > G and the TNFα -308 G > A with susceptibility to COVID-19 and clinical outcomes.
BMC medical genomics - 29 Jan 2024
Eldesouki Raghda E, Kishk Rania M, Abd El-Fadeal Noha M, Mahran Rama I, Kamel Noha, Riad Eman, Nemr Nader, Kishk Safaa M, Mohammed Eman Abdel-Moemen
Abstract excerpt
BACKGROUND: Variation in host immune responses to SARS-CoV-2 is regulated by multiple genes involved in innate viral response and cytokine storm emergence like IL-10 and TNFa gene polymorphisms. We hypothesize that IL-10; -592 C > A and - 1082 A > G and TNFa-308 G > A are associated with the risk of SARS-COV2 infections and clinical outcome. METHODS: Genotyping, laboratory and radiological investigations were...
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