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Article

RNF213 p.R4810K Variant Carriers with Intracranial Arterial Stenosis Have a Low Atherosclerotic Burden.

Journal of atherosclerosis and thrombosis - 1 Nov 2022

Ohara Mariko, Yoshimoto Takeshi, Okazaki Shuhei, Gon Yasufumi, Todo Kenichi, Sasaki Tsutomu, Takasugi Junji, Ohara Nobuyuki, Ihara Masafumi, Mochizuki Hideki

Abstract excerpt

AIM: The ring finger protein 213 gene (RNF213) p.R4810K variant is a major susceptibility gene for intracranial arterial stenosis in East Asia. We hypothesized that if intracranial arterial stenosis is induced by a non-atherosclerotic mechanism similar to moyamoya disease, the patients with RNF213 p.R4810K variant may have a lower cumulative atherosclerotic burden than the non-carriers. METHODS: A total of 112...

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Identifiers

PMID: 34955493
DOI: 10.5551/jat.63379
PMCID: PMC9623084

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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