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Article

A Targeted Association Study of Blood-Brain Barrier Gene SNPs and Brain Atrophy.

Journal of Alzheimer's disease : JAD - 1 Jan 2022

Vacher Michael, Porter Tenielle, Milicic Lidija, Bourgeat Pierrick, Dore Vincent, Villemagne Victor L, Laws Simon M, Doecke James D

Abstract excerpt

BACKGROUND: The blood-brain barrier (BBB) is formed by a high-density lining of endothelial cells, providing a border between circulating blood and the brain interstitial fluid. This structure plays a key role in protecting the brain microenvironment by restricting passage of certain molecules and circulating pathogens. OBJECTIVE: To identify associations between brain volumetric changes and a set of 355...

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Identifiers

PMID: 35253741
DOI: 10.3233/JAD-210644

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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