Article
Genome-wide recombination map construction from single sperm sequencing in cattle.
BMC genomics - 5 Mar 2022
Yang Liu, Gao Yahui, Li Mingxun, Park Ki-Eun, Liu Shuli, Kang Xiaolong, Liu Mei, Oswalt Adam, Fang Lingzhao, Telugu Bhanu P, Sattler Charles G, Li Cong-Jun, Cole John B, Seroussi Eyal, Xu Lingyang, Yang Lv, Zhou Yang, Li Li, Zhang Hongping, Rosen Benjamin D, Van Tassell Curtis P, Ma Li, Liu George E
Abstract excerpt
BACKGROUND: Meiotic recombination is one of the important phenomena contributing to gamete genome diversity. However, except for human and a few model organisms, it is not well studied in livestock, including cattle. RESULTS: To investigate their distributions in the cattle sperm genome, we sequenced 143 single sperms from two Holstein bulls. We mapped meiotic recombination events at high resolution based on...
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