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Structural Evolution of Delta (B.1.617.2) and Omicron (BA.1) Spike Glycoproteins.

International journal of molecular sciences - 4 Aug 2022

Prandi Ingrid Guarnetti, Mavian Carla, Giombini Emanuela, Gruber Cesare E M, Pietrucci Daniele, Borocci Stefano, Abid Nabil, Beccari Andrea R, Talarico Carmine, Chillemi Giovanni

Abstract excerpt

The vast amount of epidemiologic and genomic data that were gathered as a global response to the COVID-19 pandemic that was caused by SARS-CoV-2 offer a unique opportunity to shed light on the structural evolution of coronaviruses and in particular on the spike (S) glycoprotein, which mediates virus entry into the host cell by binding to the human ACE2 receptor. Herein, we carry out an investigation into the...

Topics

Angiotensin-Converting Enzyme 2
COVID-19
Glycoproteins
Humans
Mutation
Pandemics
SARS-CoV-2
Spike Glycoprotein, Coronavirus

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 35955815
DOI: 10.3390/ijms23158680
PMCID: PMC9369368

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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