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Chronic myelomonocytic leukemia: 2018 update on diagnosis, risk stratification and management

18 May 2018

Abstract excerpt

Disease overview Chronic myelomonocytic leukemia (CMML) is a clonal hematopoietic stem cell disorder with overlapping features of myelodysplastic syndromes and myeloproliferative neoplasms, with an inherent risk for leukemic transformation (∼15%‐20% over 3‐5 years). Diagnosis Diagnosis is based on the presence of sustained (>3 months) peripheral blood monocytosis (≥1 × 109/L; monocytes ≥10%), along with bone...

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PMID: 29878489
DOI: 10.1002/ajh.25104

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