Article
Cross-ancestry genetic investigation of schizophrenia, cannabis use disorder, and tobacco smoking.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology - 1 Oct 2024
Johnson Emma C, Austin-Zimmerman Isabelle, Thorpe Hayley H A, Levey Daniel F, Baranger David A A, Colbert Sarah M C, Demontis Ditte, Khokhar Jibran Y, Davis Lea K, Edenberg Howard J, Di Forti Marta, Sanchez-Roige Sandra, Gelernter Joel, Agrawal Arpana
Abstract excerpt
Individuals with schizophrenia frequently experience co-occurring substance use, including tobacco smoking and heavy cannabis use, and substance use disorders. There is interest in understanding the extent to which these relationships are causal, and to what extent shared genetic factors play a role. We explored the relationships between schizophrenia (Scz; European ancestry N = 161,405; African ancestry...
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