Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

UBE2S as a novel ubiquitinated regulator of p16 and β-catenin to promote bone metastasis of prostate cancer

1 Jan 2022

Abstract excerpt

Bone metastasis is the main site of metastasis and causes the most deaths in patients with prostate cancer (PCa). The mechanism of bone metastasis is complex and not fully clarified. By RNA sequencing and analysing key pathways in bone metastases of PCa, we found that one of the most important characteristics during PCa bone metastasis was G1/S transition acceleration caused by low protein levels of p16INK4a...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Peptidase Inhibition and Analysis
Share to Prostate Cancer Treatment and Research
Share to Ubiquitin and proteasome pathways

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 35637955
DOI: 10.7150/ijbs.72629

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

UBE2S as a novel ubiquitinated regulator of p16 and β-catenin to promote bone metastasis of prostate cancerPMID 35637955Read ↗

The long transcript of lncRNA TMPO-AS1 promotes bone metastases of prostate cancer by regulating the CSNK2A1/DDX3X complex in Wnt/β-catenin signalingSemantic proximity Read ↗

ncRNA-mediated overexpression of ubiquitin-specific proteinase 13 contributes to the progression of prostate cancer via modulating AR signaling, DNA damage repair and immune infiltrationSemantic proximity Read ↗

OTUD6A promotes prostate tumorigenesis via deubiquitinating Brg1 and ARSemantic proximity Read ↗

UBE2S interacting with TRIM21 mediates the K11-linked ubiquitination of LPP to promote the lymphatic metastasis of bladder cancerSemantic proximity Read ↗

Identification of novel key genes associated with the metastasis of prostate cancer based on bioinformatics prediction and validationSemantic proximity Read ↗

LncRNA PCBP1-AS1-mediated AR/AR-V7 deubiquitination enhances prostate cancer enzalutamide resistance.Semantic proximity Read ↗

Targeting the signalling pathways regulated by deubiquitinases for prostate cancer therapeuticsSemantic proximity Read ↗

lncRNA HOXD-AS1 Regulates Proliferation and Chemo-Resistance of Castration-Resistant Prostate Cancer via Recruiting WDR5Semantic proximity Read ↗

Identification of HCG18 and MCM3AP-AS1 That Associate With Bone Metastasis, Poor Prognosis and Increased Abundance of M2 Macrophage Infiltration in Prostate CancerSemantic proximity Read ↗

Identifying the key genes and microRNAs in prostate cancer bone metastasis by bioinformatics analysisSemantic proximity Read ↗

UBE2M promotes malignant phenotypes of prostate cancer through mediating NAA10 neddylation.Semantic proximity Read ↗

Identification of prostate cancer bone metastasis related genes and potential therapy targets by bioinformatics and in vitro experimentsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.