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Article

The genetic landscape of pancreatic head ductal adenocarcinoma in China and prognosis stratification.

BMC cancer - 18 Feb 2022

Yang Yefan, Ding Ying, Gong Yuxi, Zhao Sha, Li Mingna, Li Xiao, Song Guoxin, Zhai Boya, Liu Jin, Shao Yang, Zhu Liuqing, Pang Jiaohui, Ma Yutong, Ou Qiuxiang, Wu Xue, Zhang Zhihong

Abstract excerpt

BACKGROUND: Pancreatic ductal adenocarcinoma (PDAC) is the major subtype of pancreatic cancer and head PDACs show distinct characteristics from body/tail PDACs. With limited studies based on Asian population, the mutational landscape of Asian PDAC remains unclear. METHODS: One hundred fifty-one Chinese patients with head PDAC were selected and underwent targeted 425-gene sequencing. Genomic alterations, tumor...

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Identifiers

PMID: 35180847
DOI: 10.1186/s12885-022-09279-9
PMCID: PMC8855595

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