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Article

The single-nucleotide polymorphism rs743572 of CYP17A1 shows significant association with polycystic ovary syndrome: a meta-analysis.

Reproductive biomedicine online - 1 Nov 2021

Xu Xiqiao, Hu Kaiyue, Shi Hao, Yu Yiping, Xu Jiawei, Sun Yingpu

Abstract excerpt

Polycystic ovary syndrome (PCOS) is a multifactorial reproductive and endocrine disease, believed to be caused by aberrant steroid biosynthesis pathways involving cytochrome P450, 17α-hydroxylase (CYP17A1). This meta-analysis aimed to evaluate the association between CYP17A1 polymorphism rs743572 and PCOS risk. Studies on the CYP17A1 gene were retrieved by searching PubMed, Embase and Web of Science and...

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Asian People
Genetic Predisposition to Disease
Genotype
Polycystic Ovary Syndrome

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Polymorphism, Single Nucleotide

Steroid 17-alpha-Hydroxylase

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PMID: 34538754
DOI: 10.1016/j.rbmo.2021.06.012

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

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