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Article

The KEAP1/NRF2 Signaling Pathway in Keratinization

14 Aug 2020

Abstract excerpt

Keratinization is a tissue adaptation, but aberrant keratinization is associated with skin disorders such as ichthyoses, atopic dermatitis, psoriasis, and acne. The disease phenotype stems from the interaction between genes and the environment; therefore, an understanding of the adaptation machinery may lead to a new appreciation of pathomechanisms. The KEAP1/NRF2 signaling pathway mediates the environmental...

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PMID: 32823937
DOI: 10.3390/antiox9080751

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