Article
NTCP polymorphisms were associated with fibrosis development in patients with chronic HBV infection.
Journal of infection in developing countries - 31 Jan 2022
Su Zhenzhen, Cai Bei, Wu Xiaojuan, Li Lixin, Wei Bin, Meng Liye, Wang Lu, Wang Lanlan
Abstract excerpt
INTRODUCTION: Sodium taurocholate cotransporting polypeptide has been identified as the hepatitis B virus (HBV) entry receptor. However, information regarding the role of sodium taurocholate cotransporting polypeptide variants in the development of HBV-related advanced cirrhosis and hepatocellular carcinoma is limited. METHODOLOGY: Overall, 581 patients with chronic HBV infection were divided into the liver...
Topics
- Hepatitis B
- Hepatitis B virus
- Hepatitis B, Chronic
- Humans
- Liver Cirrhosis
- Organic Anion Transporters, Sodium-Dependent
- Polymorphism, Single Nucleotide
- Symporters
