Article
The insecticide β-Cyfluthrin induces acute arrhythmic cardiotoxicity through interaction with NaV1.5 and ranolazine reverses the phenotype.
Clinical science (London, England : 1979) - 18 Mar 2022
da Silva Maria Vitoria, Santos-Miranda Artur, Joviano-Santos Julliane V, Souza Diego Santos, Marques Leisiane Pereira, Sarmento Jaqueline Oliveira, Beserra Samuel Santos, Roman-Campos Danilo
Abstract excerpt
β-Cyfluthrin, a class II Pyrethroid, is an insecticide used worldwide in agriculture, horticulture (field and protected crops), viticulture, and domestic applications. β-Cyfluthrin may impair the function of biological systems; however, little information is available about its potential cardiotoxic effect. Here, we explored the acute toxicity of β-Cyfluthrin in isolated heart preparations and its cellular basis,...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.