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Article

SPOCK1 Promotes the Development of Hepatocellular Carcinoma

3 Feb 2022

Abstract excerpt

The extracellular matrix proteoglycan SPOCK1 is increasingly recognized as a contributor to the development and progression of cancers. Here, we study how SPOCK1, which is present in non-tumorous hepatocytes at low concentrations, promotes the development and progression of malignant hepatocellular tumors. Although SPOCK1 is an extracellular matrix proteoglycan, its concentration increases in the cytoplasm of...

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Identifiers

PMID: 35186754
DOI: 10.3389/fonc.2022.819883

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