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SPOCK: Master regulator of malignant tumors (Review)

8 Oct 2024

Abstract excerpt

SPARC/osteonectin, CWCV and Kazal‑like domain proteoglycan (SPOCK) is a family of highly conserved multidomain proteins. In total, three such family members, SPOCK1, SPOCK2 and SPOCK3, constitute the majority of extracellular matrix glycoproteins. The SPOCK gene family has been demonstrated to serve key roles in tumor regulation by affecting MMPs, which accelerates the progression of cancer epithelial‑mesenchymal...

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Cancer, Lipids, and Metabolism
Chemical Reactions and Isotopes
Radiopharmaceutical Chemistry and Applications

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 39392048
DOI: 10.3892/mmr.2024.13355

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026.

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