Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Association of GSTM1 and GSTT1 Null Genotypes with Toluene Diisocyanate-Induced Asthma.

Canadian respiratory journal - 1 Jan 2022

Lee Jong-Uk, Jeong Ji-Yeon, Kim Min Kyung, Min Sun A, Park Jong-Sook, Park Choon-Sik

Abstract excerpt

BACKGROUND: Toluene diisocyanate (TDI) causes occupational asthma by generating oxidative stress, leading to tissue injury and inflammation. Glutathione transferases (GSTs) are detoxifying enzymes that eliminate oxidative stress. We examined whether the genotypes of the GSTM1 and GSTT1 genes are associated with TDI-induced occupational asthma (TDI-OA). METHODS: The study population consisted of 26 asthmatics with...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Case-Control Studies
Share to Genetic Predisposition to Disease

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genotype

Share to Glutathione Transferase

Share to Polymorphism, Genetic

Share to Risk Factors

Source

Open in PubMed Open full text

Identifiers

PMID: 35186174
DOI: 10.1155/2022/7977937
PMCID: PMC8856815

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Association of GSTM1 and GSTT1 Null Genotypes with Toluene Diisocyanate-Induced Asthma.PMID 35186174Read ↗

Glutathione S-transferase GSTP1 is a susceptibility gene for occupational asthma induced by isocyanates.Semantic proximity Read ↗

Glutathione S-transferase genotypes and allergic responses to diisocyanate exposure.Semantic proximity Read ↗

N-Acetyltransferase genotypes as modifiers of diisocyanate exposure-associated asthma risk.Semantic proximity Read ↗

Glutathione-S-transferase gene polymorphisms (GSTT1, GSTM1, GSTP1) as increased risk factors for asthma.Semantic proximity Read ↗

The HLA DRB1*1501-DQB1*0602-DPB1*0501 Haplotype Is a Risk Factor for Toluene Diisocyanate-Induced Occupational AsthmaSemantic proximity Read ↗

The GSTP1 Ile105 Val polymorphism modifies the metabolism of toluene di-isocyanate.Semantic proximity Read ↗

Genetics of occupational asthma.Semantic proximity Read ↗

Influence of genetic factors on toluene diisocyanate-related symptoms: evidence from a cross-sectional study.Semantic proximity Read ↗

Genetic variants in antioxidant genes are associated with diisocyanate-induced asthma.Semantic proximity Read ↗

GSTT1 and GSTM1 gene polymorphisms as major risk factors for asthma in a North Indian population.Semantic proximity Read ↗

Polymorphisms of the GSTM1 and GSTT1 genes in patients with allergic diseases in the Czech population.Semantic proximity Read ↗

Role of clusterin/progranulin in toluene diisocyanate-induced occupational asthma.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.