Article
Prediction of HIV Drug Resistance by Combining Sequence and Structural Properties.
IEEE/ACM transactions on computational biology and bioinformatics - 1 Jan 2000
Khalid Zoya, Sezerman Osman Ugur
Abstract excerpt
Drug resistance is a major obstacle faced by therapist in treating HIV infected patients. The reason behind these phenomena is either protein mutation or the changes in gene expression level that induces resistance to drug treatments. These mutations affect the drug binding activity, hence resulting in failure of treatment. Therefore, it is necessary to conduct resistance testing in order to carry out HIV...
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