Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Truncated dopamine transporter's epigenetics: Heterozigosity of the grandmother rat temperates the vulnerable phenotype in second-generation offspring.

International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience - 1 Apr 2022

Pepe Martina, Calcaprina Barbara, Vaquer Francesca, Laviola Giovanni, Adriani Walter

Abstract excerpt

Behavioral phenotype differs among epigenotypes of dopamine-transporter heterozygous (DAT-HET) rats. Epigenetic regulations act through transgenerational effects, referring to phenotypic variations emerging at second or third generation. To investigate transgenerational influences exerted by maternal grandmothers, we developed breeding schemes where only the genotype of maternal grandmothers varied. HET females,...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Dopamine
Share to Dopamine Plasma Membrane Transport Proteins

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Epigenesis, Genetic

Share to Heterozygote

Share to Phenotype

Source

Identifiers

PMID: 35156234
DOI: 10.1002/jdn.10172

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Truncated dopamine transporter's epigenetics: Heterozigosity of the grandmother rat temperates the vulnerable phenotype in second-generation offspring.PMID 35156234Read ↗

Exploring transgenerational inheritance in epigenotypes of DAT heterozygous rats: Circadian anomalies and attentional vulnerability.Semantic proximity Read ↗

Inheritance of wild and truncated DAT alleles from grand-parents: Opposite transgenerational consequences on the behavioral phenotype in adolescent DAT heterozygous rats.Semantic proximity Read ↗

Dopamine-transporter heterozygous rats carrying maternal wild-type allele are more vulnerable to the development of compulsive behavior.Semantic proximity Read ↗

Maternal care of heterozygous dopamine receptor D4 knockout mice: Differential susceptibility to early-life rearing conditions.Semantic proximity Read ↗

Maternal care of heterozygous Dopamine Receptor D4 knockout mice: Differential susceptibility to early-life rearing conditionsSemantic proximity Read ↗

Unexpected effects of early-life adversity and social enrichment on the anxiety profile of mice varying in serotonin transporter genotype.Semantic proximity Read ↗

Modulation of behavioural profile and stress response by 5-HTT genotype and social experience in adulthood.Semantic proximity Read ↗

The roles of sex and serotonin transporter levels in age- and stress-related emotionality in mice.Semantic proximity Read ↗

Apomorphine susceptibility and animal models for psychopathology: genes and environment.Semantic proximity Read ↗

Genetic background, nature of event, and time of exposure to event direct the phenotypic expression of a particular genotype. A study with apomorphine-(un)susceptible Wistar rats.Semantic proximity Read ↗

The role of interindividual licking received and dopamine genotype on later-life licking provisioning in female rat offspring.Semantic proximity Read ↗

Sex-dependent adaptive changes in serotonin-1A autoreceptor function and anxiety in Deaf1-deficient mice.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.