Article

MIR-128 TARGETING PPAR-γ IMPROVES VASCULAR REMODELING IN SPONTANEOUSLY HYPERTENSIVE RATS BY REGULATING THE TLR4/NFKB INFLAMMATORY PATHWAY

2026-05-11

Abstract excerpt

<h4>OBJECTIVE</h4> This study aimed to explore the role and underlying mechanism of microRNA-128 (miR-128) in regulating vascular remodeling in spontaneously hypertensive rats (SHRs), focusing on its targeting of peroxisome proliferator-activated receptor γ (PPAR-γ) and modulation of the Toll-like receptor 4/nuclear factor-κB (TLR4/NF-κB) inflammatory pathway. <h4>METHODS</h4> All experimental procedures were ap...

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Literature Corpus work: 43a434d6-8b44-5fb9-b3f4-f8d56c2c26ee
DOI: 10.64898/2026.05.05.723109

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