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Article

CAP2 mutation leads to impaired actin dynamics and associates with supraventricular tachycardia and dilated cardiomyopathy

5 Dec 2018

Abstract excerpt

Background Dilated cardiomyopathy (DCM) is a primary myocardial disease leading to contractile dysfunction, progressive heart failure and excessive risk of sudden cardiac death. Around half of DCM cases are idiopathic, and genetic factors seem to play an important role. Aim We investigated a possible genetic cause of DCM in two consanguineous children from a Bedouin family. Methods and results Using exome...

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PMID: 30518548
DOI: 10.1136/jmedgenet-2018-105498

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