Article
Islet Lymphocytes Maintain a Stable Regulatory Phenotype Under Homeostatic Conditions and Metabolic Stress.
Frontiers in immunology - 1 Jan 2022
Whitesell Jennifer C, Lindsay Robin S, Olivas-Corral Jessica G, Yannacone Seth F, Schoenbach Mary H, Lucas Erin D, Friedman Rachel S
Abstract excerpt
T cells and B cells have been identified in human and murine islets, but the phenotype and role of islet lymphocytes is unknown. Resident immune populations set the stage for responses to inflammation in the islets during homeostasis and diabetes. Thus, we sought to identify the phenotype and effector function of islet lymphocytes to better understand their role in normal islets and in islets under metabolic...
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