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Article

Dynamic host immune response in virus-associated cancers

22 Mar 2019

Abstract excerpt

Abstract Viruses drive carcinogenesis in human cancers through diverse mechanisms that have not been fully elucidated but include promoting immune escape. Here we investigated associations between virus-positivity and immune pathway alteration for 2009 tumors across six virus-related cancer types. Analysis revealed that for 3 of 72 human papillomavirus (HPV)-positive head and neck squamous cell carcinoma (HNSC)...

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PMID: 30911684
DOI: 10.1038/s42003-019-0352-3

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