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Targeting cellular senescence to combat cancer and ageing

8 Jun 2022

Abstract excerpt

Senescence is a complex cellular process that is implicated in various physiological and pathological processes. It is characterized by a stable state of cell growth arrest and by a secretome of diverse pro-inflammatory factors, chemokines and growth factors. In this review, we summarize the context-dependent role of cellular senescence in ageing and in age-related diseases, such as cancer. We discuss current...

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PMID: 35674055
DOI: 10.1002/1878-0261.13266

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