Article
In-silico study of influence of HLA heterogeneity on CTL responses across ethnicities to SARS-CoV-2.
Human immunology - 1 Dec 2022
Rao Vishal, Chandra Nagasuma
Abstract excerpt
Differences in outcome to COVID-19 infection in different individuals is largely attributed to genetic heterogeneity leading to differential immune responses across individuals and populations. HLA is one such genetic factor that varies across individuals leading to differences in how T-cell responses are triggered against SARS-CoV-2, directly influencing disease susceptibility. HLA alleles that influence...
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