Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Bismuth Drugs Reverse Tet(X)-Conferred Tigecycline Resistance in Gram-Negative Bacteria

9 Feb 2022

Abstract excerpt

Recently, high-level tigecycline resistance mediated by tet (X4) and its variants represents a serious challenge for global public health. Antibiotic adjuvant strategy that enhances the activity of the existing antibiotics by using nonantibiotic drugs offers a distinct approach to combat the antibiotic resistance crisis. In this study, we found that bismuth drugs involve bismuth nitrate, a compound previously...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Antibiotic Resistance in Bacteria
Share to Pharmaceutical and Antibiotic Environmental Impacts
Share to Pneumocystis jirovecii pneumonia detection and treatment

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 35138168
DOI: 10.1128/spectrum.01578-21

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Bismuth Drugs Reverse Tet(X)-Conferred Tigecycline Resistance in Gram-Negative BacteriaPMID 35138168Read ↗

Anti-HIV agent azidothymidine decreases Tet(X)-mediated bacterial resistance to tigecycline in Escherichia coliSemantic proximity Read ↗

Evolutionary Trajectory of the Tet(X) Family: Critical Residue Changes towards High-Level Tigecycline ResistanceSemantic proximity Read ↗

Synergistic efficacy of tigecycline combined with apramycin against <i>tet</i> (X)-harboring <i>Acinetobacter spp.</i>Semantic proximity Read ↗

Tigecycline - how powerful is it in the fight against antibiotic-resistant bacteria?Semantic proximity Read ↗

Source tracking and global distribution of the mobilized tigecycline resistant gene <i>tet</i> (X)Semantic proximity Read ↗

Comparison of <i>tet</i> (X4)-containing contigs from metagenomic sequencing data with plasmid sequences of isolates from a cohort of healthy subjectsSemantic proximity Read ↗

Genetic diversity and characteristics of high-level tigecycline resistance Tet(X) in Acinetobacter species.Semantic proximity Read ↗

Mechanistic Insights into Crosstalk of Tet(X) and MCR-1, Two Resistance Enzymes Co-produced by A Single PlasmidSemantic proximity Read ↗

Preliminary view of the global distribution and spread of the tet(X) family of tigecycline resistance genesSemantic proximity Read ↗

Presence of Mobile Tigecycline Resistance Gene <i>tet</i> (X4) in Clinical Klebsiella pneumoniaeSemantic proximity Read ↗

Discovery and development of DNA polymerase IIIC inhibitors to treat Gram-positive infectionsSemantic proximity Read ↗

Co‐production of Tet(X) and MCR ‐1, two resistance enzymes by a single plasmidSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.