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Article

Co‐production of Tet(X) and MCR ‐1, two resistance enzymes by a single plasmid

9 Feb 2021

Abstract excerpt

Tigecycline and colistin are few of 'last-resort' antibiotic defences used in anti-infection therapies against carbapenem-resistant bacterial pathogens. The successive emergence of plasmid-borne tet(X) tigecycline resistance mechanism and mobile colistin resistance (mcr) determinant, renders them clinically useless. Here, we report that co-carriage of tet(X6) and mcr-1 gives co-resistance to both classes of...

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Identifiers

PMID: 33559156
DOI: 10.1111/1462-2920.15425

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