Article
Tigecycline - how powerful is it in the fight against antibiotic-resistant bacteria?
Medicina (Kaunas, Lithuania) - 1 Jan 2010
Seputiene Vaida, Povilonis Justas, Armalyte Julija, Suziedelis Kestutis, Pavilonis Alvydas, Suziedeliene Edita
Abstract excerpt
Tigecycline is a semisynthetic analogue of earlier tetracyclines and represents the first member of a novel class of antimicrobials - glycylcyclines - recently approved for clinical use. It is active against a broad range of gram-negative and gram-positive bacterial species including clinically important multidrug-resistant nosocomial and community-acquired bacterial pathogens. The exact molecular basis of...
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