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Article

Variations within Toll-like receptor (TLR) and TLR signaling pathway-related genes and their synergistic effects on the risk of Guillain-Barré syndrome.

Journal of the peripheral nervous system : JPNS - 1 Jun 2022

Dutta Debprasad, Nagappa Madhu, Sreekumaran Nair Binu V, Das Sumit Kumar, Wahatule Rahul, Sinha Sanjib, Vasanthapuram Ravi, Taly Arun B, Debnath Monojit

Abstract excerpt

Guillain-Barré syndrome (GBS) is the commonest post-infectious polyradiculopathy. Although genetic background of the host seems to play an important role in the susceptibility to GBS, genes conferring major risk are not yet known. Dysregulation of Toll-like receptor (TLR) molecules exacerbates immune-inflammatory responses and the genetic variations within TLR pathway-related genes contribute to differential risk...

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PMID: 35138004
DOI: 10.1111/jns.12484

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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