Efficient analysis of large-scale genome-wide data with two R packages: bigstatsr and bigsnpr.

Abstract excerpt

Motivation: Genome-wide datasets produced for association studies have dramatically increased in size over the past few years, with modern datasets commonly including millions of variants measured in dozens of thousands of individuals. This increase in data size is a major challenge severely slowing down genomic analyses, leading to some software becoming obsolete and researchers having limited access to diverse...

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