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Article

Including dominance effects in the prediction model through locus-specific weights on heterozygous genotypes can greatly improve genomic predictive abilities.

Heredity - 1 Mar 2022

Liu Tianfei, Luo Chenglong, Ma Jie, Wang Yan, Shu Dingming, Qu Hao, Su Guosheng

Abstract excerpt

The dominance effect is considered to be a key factor affecting complex traits. However, previous studies have shown that the improvement of the model, including the dominance effect, is usually less than 1%. This study proposes a novel genomic prediction method called CADM, which combines additive and dominance genetic effects through locus-specific weights on heterozygous genotypes. To the best of our...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 35132207
DOI: 10.1038/s41437-022-00504-6
PMCID: PMC8897419

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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