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Identification of targetable kinases in idiopathic pulmonary fibrosis

7 Feb 2022

Abstract excerpt

BACKGROUND: Tyrosine kinase activation plays an important role in the progression of pulmonary fibrosis. In this study, we analyzed the expression of 612 kinase-coding and cancer-related genes using next-generation sequencing to identify potential therapeutic targets for idiopathic pulmonary fibrosis (IPF). METHODS: Thirteen samples from five patients with IPF (Cases 1-5) and eight samples from four patients...

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Share to Cancer Mechanisms and Therapy
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PMID: 35130915
DOI: 10.1186/s12931-022-01940-y

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