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Article

PTK2-associated gene signature could predict the prognosis of IPF

6 Dec 2023

Abstract excerpt

Idiopathic pulmonary fibrosis (IPF) is a progressive and fatal lung disease with a poor prognosis. Current/available clinical prediction tools have limited sensitivity and accuracy when evaluating clinical outcomes of IPF. Research has shown that focal adhesion kinase (FAK), produced by the protein tyrosine kinase 2 (PTK2) gene, is crucial in IPF development. FAK activation is a characteristic of lesional...

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Share to Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
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PMID: 38053045
DOI: 10.1186/s12931-023-02582-4

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