Integrative Multi-omics and machine learning analysis of sphingolipid-associated molecular stratification identifies diagnostic and prognostic signatures in idiopathic pulmonary fibrosis

Abstract excerpt

Abstract Background Emerging evidence suggests that sphingolipid metabolism is involved in respiratory diseases, including idiopathic pulmonary fibrosis (IPF). This study aimed to evaluate the diagnostic and prognostic value of sphingolipid-related genes in IPF and to identify potential sphingolipid-associated biomarkers. Methods Sphingolipid-related genes were obtained from the GeneCards database. Non-negative ma...

Topics

Open a Topic to create a Post that cites this publication.

• Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis
• Sphingolipid Metabolism and Signaling
• Spondyloarthritis Studies and Treatments

Identifiers and source

Literature Corpus work

3a00aadb-2d94-55f2-93c1-ad6c1900ee2f

DOI

10.1186/s13023-026-04563-4