Article
Clinicopathologic and protein markers distinguishing the "polymerase epsilon exonuclease" from the "copy number low" subtype of endometrial cancer.
Journal of gynecologic oncology - 1 May 2022
Kim Kidong, Hwangbo Suhyun, Kim Hyojin, Kim Yong Beom, No Jae Hong, Suh Dong Hoon, Park Taesung
Abstract excerpt
OBJECTIVE: The need to perform genetic sequencing to diagnose the polymerase epsilon exonuclease (POLE) subtype of endometrial cancer (EC) hinders the adoption of molecular classification. We investigated clinicopathologic and protein markers that distinguish the POLE from the copy number (CN)-low subtype in EC. METHODS: Ninety-one samples (15 POLE, 76 CN-low) were selected from The Cancer Genome Atlas EC...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
