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Dynamic Epigenetic Changes During Antidepressant Pharmacotherapy in Major Depressive Disorder

2025-11-20

Abstract excerpt

Although antidepressants remain the main pharmacological treatment for major depressive disorder (MDD), therapeutic response varies, highlighting the need for molecular markers that predict treatment response, as well as insights into the biological processes underlying antidepressant efficacy. Candidate-gene and cross-sectional epigenome-wide association studies (EWAS) have reported DNA methylation signatures ass...

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Literature Corpus work
574b018c-be0b-5e7d-a12e-81f31904099a
DOI
10.1101/2025.11.20.688229
Open publication

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Dynamic Epigenetic Changes During Antidepressant Pharmacotherapy in Major Depressive DisorderDOI 10.1101/2025.11.20.688229
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