Article
Genome-wide meta-analysis of alcohol use disorder in East Asians.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology - 1 Sept 2022
Zhou Hang, Kalayasiri Rasmon, Sun Yan, Nuñez Yaira Z, Deng Hong-Wen, Chen Xiang-Ding, Justice Amy C, Kranzler Henry R, Chang Suhua, Lu Lin, Shi Jie, Sanichwankul Kittipong, Mutirangura Apiwat, Malison Robert T, Gelernter Joel
Abstract excerpt
Alcohol use disorder (AUD) is a leading cause of death and disability worldwide. Genome-wide association studies (GWAS) have identified ~30 AUD risk genes in European populations, but many fewer in East Asians. We conducted GWAS and genome-wide meta-analysis of AUD in 13,551 subjects with East Asian ancestry, using published summary data and newly genotyped data from five cohorts: (1) electronic health record...
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