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Article

FLT3 mutational analysis in acute myeloid leukemia: Advantages and pitfalls with different approaches.

Blood reviews - 1 Jul 2022

Cumbo Cosimo, Tarantini Francesco, Anelli Luisa, Zagaria Antonella, Specchia Giorgina, Musto Pellegrino, Albano Francesco

Abstract excerpt

FMS-like tyrosine kinase 3 (FLT3) is one of the most closely studied genes in blood diseases. Numerous methods have been adopted for analyses, mainly in acute myeloid leukemia (AML) diagnostic work-up. According to international recommendations, the current gold standard approach allows FLT3 canonical mutations to be investigated, providing the main information for risk assessment and treatment choice. However,...

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PMID: 35086749
DOI: 10.1016/j.blre.2022.100928

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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