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Article

Whole Exome Sequencing in Early-onset Systemic Lupus Erythematosus

15 Jul 2018

Abstract excerpt

Objective. Systemic lupus erythematosus (SLE) is a multisystem autoimmune disorder. Early-onset, familial, and/or syndromic SLE may reveal monogenic pathologies. The aim of this study was to examine genetic associations in patients with early-onset or familial SLE. Methods. We enrolled 7 SLE cases (from different families) with disease onset ≤ 5 years of age and family history consistent with an autosomal...

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PMID: 30008451
DOI: 10.3899/jrheum.171358

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