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Article

Patient-individual phenotypes of glioblastoma stem cells are conserved in culture and associate with radioresistance, brain infiltration and patient prognosis.

International journal of cancer - 15 May 2022

Ganser Katrin, Eckert Franziska, Riedel Andreas, Stransky Nicolai, Paulsen Frank, Noell Susan, Krueger Marcel, Schittenhelm Jens, Beck-Wödl Stefanie, Zips Daniel, Ruth Peter, Huber Stephan M, Klumpp Lukas

Abstract excerpt

Identification of prognostic or predictive molecular markers in glioblastoma resection specimens may lead to strategies for therapy stratification and personalized treatment planning. Here, we analyzed in primary glioblastoma stem cell (pGSC) cultures the mRNA abundances of seven stem cell (MSI1, Notch1, nestin, Sox2, Oct4, FABP7 and ALDH1A3), and three radioresistance or invasion markers (CXCR4, IKCa and BKCa )....

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Identifiers

PMID: 35085407
DOI: 10.1002/ijc.33950

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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