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Article

Noise-augmented directional clustering of genetic association data identifies distinct mechanisms underlying obesity.

PLoS genetics - 1 Jan 2022

Grant Andrew J, Gill Dipender, Kirk Paul D W, Burgess Stephen

Abstract excerpt

Clustering genetic variants based on their associations with different traits can provide insight into their underlying biological mechanisms. Existing clustering approaches typically group variants based on the similarity of their association estimates for various traits. We present a new procedure for clustering variants based on their proportional associations with different traits, which is more reflective of...

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Identifiers

PMID: 35085229
DOI: 10.1371/journal.pgen.1009975
PMCID: PMC8794082

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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