Article
T7 Endonuclease I-mediated voltammetric detection of KRAS mutation coupled with horseradish peroxidase for signal amplification.
Mikrochimica acta - 27 Jan 2022
Chowdhury Pinky, Cha Byung Seok, Kim Seokjoon, Lee Eun Sung, Yoon Taehwi, Woo Jisu, Park Ki Soo
Abstract excerpt
Rapid and selective sensing of KRAS gene mutation which plays a crucial role in the development of colorectal, pancreatic, and lung cancers is of great significance in the early diagnosis of cancers. In the current study, we developed a simple electrochemical biosensor by differential pulse voltammetry technique for the specific detection of KRAS mutation that uses the mismatch-specific cleavage activity of...
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