Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

CXCL12/CXCR4 axis gene variants contribute to an increased vulnerability to HPV infection and cervical oncogenesis.

Journal of cancer research and clinical oncology - 1 Apr 2022

Okuyama Nádia Calvo Martins, Cezar-Dos-Santos Fernando, Trugilo Kleber Paiva, Esposito Aline, Guembarovski Roberta Losi, Couto-Filho José d'Oliveira, Watanabe Maria Angelica Ehara, de Oliveira Karen Brajão

Abstract excerpt

PURPOSE: Every year, more than half a million women are diagnosed with cervical cancer (CC). Individual factors may contribute to the cervical cancer development, such as immunogenetic variation. CXCL12/CXCR4 axis is involved in tumor progression and aggressiveness. In the present study, we aimed to investigate a possible association between two single-nucleotide variants (CXCL12 rs1801157 and CXCR4 rs2228014)...

Read the complete abstract on PubMed

Topics

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share this publication in a Topic to start or enrich a Post.

Share to Alleles
Share to Carcinogenesis
Share to Chemokine CXCL12
Share to Gene Frequency
Share to Genetic Predisposition to Disease
Share to Papillomavirus Infections
Share to Receptors, CXCR4
Share to Uterine Cervical Neoplasms

Source

Identifiers

PMID: 35083551
DOI: 10.1007/s00432-021-03884-0

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

CXCL12/CXCR4 axis gene variants contribute to an increased vulnerability to HPV infection and cervical oncogenesis.PMID 35083551Read ↗

Genetic Variants of Interleukin-8 and Interleukin-16 and Their Association with Cervical Cancer RiskSemantic proximity Read ↗

Genetic variation in CXCL12 and risk of cervical carcinoma: a population-based case-control study.Semantic proximity Read ↗

Gene Variations of Chemokine and Chemokine Receptor CXCL12/CXCR4 in Lung Cancer.Semantic proximity Read ↗

Association of the CXCL12 rs1801157 Polymorphism with Breast Cancer Risk: A Meta-Analysis.Semantic proximity Read ↗

CXCL12 rs266085 and TNF-α rs1799724 polymorphisms and susceptibility to cervical cancer in a Chinese population.Semantic proximity Read ↗

Associations of CXCL12 polymorphisms with clinicopathological features in breast cancer: a case-control study.Semantic proximity Read ↗

Combinational polymorphisms of seven CXCL12-related genes are protective against breast cancer in Taiwan.Semantic proximity Read ↗

CXCL12 chemokine and CXCR4 receptor: association with susceptibility and prognostic markers in triple negative breast cancer.Semantic proximity Read ↗

The G801A polymorphism in the CXCL12 gene and risk of breast carcinoma: evidence from a meta-analysis including 2,931 subjects.Semantic proximity Read ↗

The Value of CXCL1, CXCL2, CXCL3, and CXCL8 as Potential Prognosis Markers in Cervical Cancer: Evidence of E6/E7 from HPV16 and 18 in Chemokines RegulationSemantic proximity Read ↗

CXCL12 and CXCR4 polymorphisms and expressions in peripheral blood from patients of hepatocellular carcinoma.Semantic proximity Read ↗

Higher circulating levels of chemokine CXCL10 in patients with breast cancer: Evaluation of the influences of tumor stage and chemokine gene polymorphism.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.