Article
CXCL12 and CXCR4 polymorphisms and expressions in peripheral blood from patients of hepatocellular carcinoma.
Future oncology (London, England) - 1 Jun 2018
Qin Li-Feng, Qin Jin-Mei, Zhang Ji-Qiao, Lv Xiao-Ping, Huang Li-Yi, Wang Jing-Jing
Abstract excerpt
AIM: To determine if CXCL12 (rs1801157) and CXCR4 (rs2228014) polymorphisms are associated with hepatocellular carcinoma (HCC) susceptibility, and detect their expressions in peripheral blood. METHODS: 206 HCC patients, 252 chronic hepatitis B patients, 221 liver cirrhosis patients and 275 healthy volunteers were recruited. Genes CXCL12 and CXCR4 were amplified and genotyped. Their expression in peripheral blood...
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