Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

CXCL12 chemokine and CXCR4 receptor: association with susceptibility and prognostic markers in triple negative breast cancer.

Molecular biology reports - 1 Oct 2018

Guembarovski Alda Losi, Guembarovski Roberta Losi, Hirata Bruna Karina Banin, Vitiello Glauco Akelinghton Freire, Suzuki Karen Mayumi, Enokida Mayara Tiemi, Watanabe Maria Angelica Ehara, Reiche Edna Maria Vissoci

Abstract excerpt

CXCL12/CXCR4 signaling has been implicated in breast carcinogenesis, and genetic polymorphisms in these molecules have been associated with different types of cancer. The present study analyzed genetic polymorphisms in CXCL12 (rs1801157, G > A) and CXCR4 (rs2228014, C > T) and CXCR4 immunostaining in tumor tissues from patients with triple negative breast cancer (TNBC) aiming to evaluate their possible role in...

Read the complete abstract on PubMed

Topics

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share this publication in a Topic to start or enrich a Post.

Share to Biomarkers, Tumor
Share to Chemokine CXCL12
Share to Gene Frequency
Share to Genetic Association Studies
Share to Lymphatic Metastasis
Share to Prognosis
Share to Receptors, CXCR4
Share to Triple Negative Breast Neoplasms

Source

Identifiers

PMID: 29926386
DOI: 10.1007/s11033-018-4215-7

Genes

CXCR4
CXCL12

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

CXCL12 chemokine and CXCR4 receptor: association with susceptibility and prognostic markers in triple negative breast cancer.PMID 29926386Read ↗

Associations of CXCL12 polymorphisms with clinicopathological features in breast cancer: a case-control study.Semantic proximity Read ↗

Genetic Polymorphism and Expression of CXCR4 in Breast Cancer.Semantic proximity Read ↗

Combined effects of IL-8 and CXCR2 gene polymorphisms on breast cancer susceptibility and aggressiveness.Semantic proximity Read ↗

Association of the CXCL12 rs1801157 Polymorphism with Breast Cancer Risk: A Meta-Analysis.Semantic proximity Read ↗

CXCL12 rs1801157 polymorphism and expression in peripheral blood from breast cancer patients.Semantic proximity Read ↗

CXCL12/CXCR4 axis gene variants contribute to an increased vulnerability to HPV infection and cervical oncogenesis.Semantic proximity Read ↗

CXCL12 rs1801157 polymorphism in patients with breast cancer, Hodgkin's lymphoma, and non-Hodgkin's lymphoma.Semantic proximity Read ↗

CXCL12 and CXCR4 polymorphisms and expressions in peripheral blood from patients of hepatocellular carcinoma.Semantic proximity Read ↗

Combinational polymorphisms of seven CXCL12-related genes are protective against breast cancer in Taiwan.Semantic proximity Read ↗

Higher circulating levels of chemokine CXCL10 in patients with breast cancer: Evaluation of the influences of tumor stage and chemokine gene polymorphism.Semantic proximity Read ↗

Allelic variants and immunostaining profile in CXCL12/CXCR4 axis: An investigation of association with prognosis in prostate cancer.Semantic proximity Read ↗

The rs1008562, rs2234671, and rs3138060 polymorphisms of the CXCR1 gene are associated with breast cancer risk in a Mexican population.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.